Saline Infusion Sonogram (SIS)

In a saline infusion sonogram, a small amount of saline solution is inserted into the uterus via a catheter while the doctor or technician views the uterus with a transvaginal ultrasound. The saline solution pushes the walls of the uterus apart, allowing a doctor or technician to more clearly visualize polyps, fibroids, adhesions, cancerous lesions, and other anomalies. These anomalies may be missed using ultrasound alone.

The best time to do a SIS is early in your cycle, shortly after your period has ended. The procedure is minimally invasive and requires no advanced preparation. When the saline is inserted into the uterus, you may feel some slight cramping. After the SIS, you may experience some discharge and/or slight spotting, so you may want to have a panty liner on hand.

While a SIS will help your doctor better see what is happening in your uterus, it will not help your doctor visualize your fallopian tubes. If there are concerns about your tubes, you will want to discuss whether a SIS or hysterosalpingogram (HSG) is the best imaging study for you.

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